Mouse Models for Drug Discovery (e-book) (used book) | bookbook.eu

Description

1. Genetically Defined Strains in Drug Development and Toxicity Testing

Michael F.W. Festing

2. Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods

Benjamin E. Low, Peter M. Kutny, and Michael V. Wiles

3. Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice

Benjamin E. Low, Rob A. Taft, and Michael V. Wiles

4. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells

Suheyla Hasgur, Ken Edwin Aryee, Leonard D. Shultz, Dale L. Greiner, and Michael A. Brehm

5. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens

Markus von Schaewen, Gabriela Hrebikova, and Alexander Ploss

6. Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies

Derry C. Roopenian, Gregory J. Christianson, Gabriele Proetzel, and Thomas J. Sproule

7. A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics

Benjamin E. Low and Michael V. Wiles

8. Germ-Free Mice Model for Studying Host-Microbial Interactions

Yogesh Bhattarai and Purna Kashyap

9. Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans

David V. Serreze, Marijke Niens, John Kulik, and Teresa P. DiLorenzo

10. Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery

Helene Baribault

11. Cholesterol Absorption and Metabolism

Philip N. Howles

12. Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening

John P. Sundberg, Kathleen A. Silva, Lloyd E. King, Jr, and C. Herbert Pratt

13. Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research

Cong Peng and Shaoguang Li

14. Murine Model for Colitis-Associated Cancer of the Colon

Ashley J. Snider, Agnieszka B. Bialkowska, Amr M. Ghaleb, Vincent W. Yang, Lina M. Obeid, and Yusuf A. Hannun

15. Mouse Models for Studying Depression-Like States and Antidepressant Drugs

Carisa L. Bergner, Amanda N. Smolinsky, Peter C. Hart, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff

16. Experimental Models of Anxiety for Drug Discovery and Brain Research

Peter C. Hart, Carisa L. Bergner, Amanda N. Smolinsky, Brett D. Dufour, Rupert J. Egan, Justin L. LaPorte, and Allan V. Kalueff