Molecular Profiling (e-book) (used book) | bookbook.eu

Description

Contents

Preface

Contributors

1. Tumor Staging and Grading: A Primer

Stacy M. Cowherd

2. Clinical Trial Design in the Age of Molecular Profiling

Alexander Spira and Kirsten H. Edmiston

3. Personalized Medicine: Ethics for Clinical Trials

G. Terry Sharrer

4. Reduction of Preanalytical Variability in Specimen Procurement for Molecular Profiling

Virginia Espina and Claudius Mueller

5. The Human Side of Cancer Biobanking

Eoin Gaffney, Deirdre Madden, and Geraldine A. Thomas

6. Introduction to Genomics

Luca Del Giacco and Cristina Cattaneo

7. Genomic Profiling: cDNA arrays and oligoarrays

Francesco Gorreta, Walter Carbone, Dagania Barzhagi

8. Genome wide methylation profiling in archival formalin fixed paraffin embedded (FFPE) tissue samples

J. Keith Killian, Robert L. Walker, Sven Bilke, Yidong Chen, Sean Davis, Robert Cornelison, William I. Smith, and Paul S. Meltzer

9. An Overview of microRNA Methods: Expression Profiling and Target Identification

Sinéad M Smith and David W Murray

10. Antibody Validation by Western Blotting

Michele Signore and K. Alex Reeder

11. Laser Capture Microdissection: Arcturus^XT infra-red capture and UV cutting methods

Rosa I. Gallagher, Steven R. Blakely, Lance A. Liotta, and Virginia Espina

12. Antibody microarrays: Analysis of Cystic Fibrosis

Catherine E. Jozwik, Harvey B. Pollard, Meera Srivastava, Ofer Eidelman, QingYuan Fan, Thomas N. Darling, and Pamela L. Zeitlin

13. Tissue Microarrays As A Tool In The Discovery & Validation Of Predictive Biomarkers

Stephen M. Hewitt

14. Reverse phase protein microarrays

Mariaelena Pierobon, Francesca Galdi, Noemi Moroni, and Emanuel F. Petricoin III

15. Serum Low Molecular Weight Protein Fractionation for Biomarker Discovery

Amy VanMeter, Serena Camerini, Maria Letizia Polci, Alessandra Tessitore, Nishant Trivedi, Michael Heiby, Jonathan Hansen, and Weidong Zhou

16. Mass spectrometry based biomarker discovery

Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo

17. Mitochondrial Proteome: Toward The Detection and Profiling of Disease Associated Alterations

Paul C. Herrmann and E. Clifford Herrmann

18. Adult Neural Stem Cells: Isolation and Propagation

Jamin M. Lechter and Daniel N. Cox

19. Evanescent Wave Imaging: An Introduction to Total Internal Reflection Fluorescence Microscopy (TIRF)

Bryan A. Millis

20. Construction and Hyperspectral Imaging of Quantum Dot Lysate Arrays

Kevin P. Rosenblatt, Michael Huebschman, and Harold R. Garner

21. Microarray Data Analysis: Comparing Two Population Means

Jianghong Deng, Valerie S. Calvert and Mariaelena Pierobon

22. Bioinformatics/Biostatistics: microarray analysis

Gabriel S. Eichler

23. Structure-based functional design of drugs: from target to lead compound

Amy C. Anderson

24. Personalized Medicine: Changing the Paradigm of Drug Development

Robin Couch and Bryan T. Mott

25. Grant Writing Tips for the First Time Applicant

Lindsay Wescott and Michael Laskofski

26. Inventions and Patents: A practical tutorial

J. Lille Tidwell and Lance Liotta

27. Regulatory Approval Pathways for Molecular Diagnostic Technology

Lance Liotta and Emanuel Petricoin

28. Small business development for molecular diagnostics

Athanasia Anagnostou and Lance Liotta