Methods for the Discovery and Characterization of G Protein-Coupled Receptors (e-book) (used book) | bookbook.eu

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Part I: The G Protein-Coupled Receptor in the Genome

1. In Silico Identification of Novel G Protein-Coupled Receptors

Matthew N. Davies, David E. Gloriam, and Darren R. Flower

2. Alternative Pre-mRNA Splicing of G Protein-Coupled Receptors

Ying-Xian Pan, Steven Grinnell, and Gavril W. Pasternak

3. Detecting Polymorphisms in G Protein-Coupled Receptor Genes

Dmitri Proudnikov, Vadim Yuferov, and Mary Jeanne Kreek

4. Regulation of the Transcription of G Protein-Coupled Receptor Genes

Cheol Kyu Hwang, Ping-Yee Law, Li-Na Wei, and Horace H. Loh

5. Deciphering the Evolution of G Protein-Coupled Receptors in Vertebrates

Craig W. Stevens

Part II: The Trafficking of G Protein-Coupled Receptors

6. A New Approach to Visualize Endogenously Expressed G Protein-Coupled Receptors in Tissues and Living Cells

Brigitte L Kieffer and Grégory Scherrer

7. Post-Translational Regulation of G Protein-Coupled Receptors

Yu Qiu and Ping-Yee Law

8. Discovering G Protein-Coupled Receptor Motifs Mediating Export from the Endoplasmic Reticulum

Chunmin Dong and Guangyu Wu

9. Identifying G Protein-Coupled Receptor Escorts, Chaperones, and Intracellular Tethers Regulating Receptor Density at the Cell Surface

Stefano Marullo, Liliana Pardo Lopez, and Lamia Achour

10. A Novel Method for Determining the Kinetics of G Protein-Coupled Receptor Plasma Membrane Expression

Gregory W. Sawyer

Part III: The G Protein-Coupled Receptor on the Membrane

11. Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines

Kathryn A. Seely and Paul L. Prather

12. Novel Assay Technologies for the Discovery of G Protein-Coupled Receptor Drugs

Elisa Alvarez-Curto, Richard J. Ward, and Graeme Milligan

13. Discovering Cell-Type-Specific Patterns of G Protein-Coupled Receptor Phosphorylation

Kok Choi Kong, Andrew B. Tobin, and Adrian J. Butcher

14. Quantifying Allosteric Modulation of G Protein-Coupled Receptors

Frederick J. Ehlert and Hinako Suga

15. Experimental Designs for the Study of Receptor-Receptor Interactions

Dennis Paul

Part IV: The Regulation of G Protein-Coupled Receptors

16. Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization

Chris P. Bailey and Eamonn Kelly

17. Detecting the Role of Arrestins in G-Protein Coupled Receptor Regulation

Laura M. Bohn and Patricia H. McDonald

18. Characterizing Molecular Mobility and Membrane Interactions of G Protein-Coupled Receptors

Vladana Vukojevic, Yu Ming, and Lars Terenius

19. Using RNA Interference to Downregulate G Protein-Coupled Receptors

Philippe Sarret, Louis Doré-Savard, Pascal Tétreault, Valérie Bégin-Lavallée, Marc-André Dansereau, and Nicolas Beaudet

20. Upregulating G Protein-Coupled Receptors with Receptor Antagonists

Ellen M. Unterwald