Macromolecular Anticancer Therapeutics (e-book) (used book) | bookbook.eu

Description

I. Synthetic polymer-based anticancer prodrugs

Jindrich Kopecek (Departments of Pharmaceutics and Pharmaceutical Chemistry and of Bioengineering, University of Utah, Salt Lake City, Utah 84112)

HPMA-anticancer drug conjugates

Richard B. Greenwald (Enzon Pharmaceuticals, Inc., 20 Kingsbridge Road, Piscataway, New Jersey 00854)

Poly(ethylene glycol)-anticancer drug conjugates

Chun Li (Department of Experimental Diagnostic Imaging, Box 59, The University of Texas, M.D. Anderson Cancer Center,

1515 Holcombe Blvd., Houston, TX 77030, USA)

Poly(L-glutamic acid)-anticancer drug conjugates

II. Natural polymer-based anticancer prodrugs

Felix Kratz (Department of Medical Oncology, Clinical Research, Tumor Biology Center, Breisacher Straße 117, D-79106 Freiburg, Federal Republic of Germany)

Protein-based anticancer conjugates

Andrew V. Schally (Endocrine, Polypeptide and Cancer Institute, Veterans Affairs Medical Center, New Orleans, Louisiana)

Peptide and peptide hormone anticancer therapeutics

Yoshiharu Machida (Department of Drug Delivery Research, Hoshi University; 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan)

Chitosan and other polysaccharide anticancer conjugates

III. Antibody-directed cancer therapy

John R. Desjarlais

Xencor, Inc. CA 91016, United States

Engineering of antitumor antibodies

Victor S. Goldmacher (ImmunoGen Inc., 128 Sidney Street, Cambridge, MA 02139-4239, USA)

Antibody-anticancer drug conjugates

David M. Goldenberg (Garden State Cancer Center, Center for Molecular Medicine and Immunology, Belleville, NJ 07109, USA.)

Immunoconjugate and radioimmunoconjugate anticancer therapeutics

Kenneth D. Bagshawe (Imperial College London, Department of Medical Oncology, Charing Cross Campus, Fulham Palace Road, London W6 8RF, UK.)

Antibody-directed enzyme prodrug anticancer therapeutics

Paul M. Harari (University of Wisconsin Medical School and Comprehensive Cancer Center, Madison, WI 53792, USA.)

EGFR-directed monoclonal antibodies

Gabriel N. Hortobagyi (Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX. usa)

Her2/neu-directed antibodies

John M. Kirkwood (Division of Hematology-Oncology, Department of Medicine, Hillman Cancer Center, Pittsburgh, PA 15232)

CTLA-4-directed monoclonal antibodies

Dario Neri (Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland)

Antibodies directed to tumor vasculature

IV. Lipid-based anticancer prodrugs

L. Harivardhan Reddy, Patrick Couvreur (Physicochimie, Pharmacotechnie et Biopharmacie, Faculty of Pharmacy, Universite Paris-Sud XI, Chatenay-Malabry, France)

Lipid-based prodrugs of anti-metabolite anticancer agents

Mitsuru Hashida (Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan)

Lipid-based prodrugs of non-anti-metabolite anticancer agents

V. Macromolecular nucleic acid therapeutics

Ernst Wagner (Pharmaceutical Biology-Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universitaet, Butenandtstr. 5-13, D-81377, Muenchen, Germany)

Macromolecular nucleic acid therapeutics

Uwe Zangemeister-Wittke (Department of Pharmacology, University of Bern, Bern, Switzerland.)

Antisense oligonucleotides

Brett P. Monia (Isis Pharmaceuticals, California 92008, USA)

Therapeutic MicroRNAs

Mark A. Behlke (Integrated DNA Technologies Inc., Coralville, IA 52241, USA)

Therapeut