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This book explains key aspects of the remarkable progress that has been made towards understanding how drugs can bind specifically to nucleic acids, and thus underpin the endeavour to make gene targeting a reality. The binding of drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.
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This book explains key aspects of the remarkable progress that has been made towards understanding how drugs can bind specifically to nucleic acids, and thus underpin the endeavour to make gene targeting a reality. The binding of drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.
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