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DNA-Encoded Chemical Libraries
328,40 € 
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Preface...Table of Contents...Contributing Authors... 1. Library Synthesis: Building Block Selection, Handling, and TrackingKatelyn J. Billings and Melissa C. Grenier-Davies 2. Library Synthesis: Building Block ValidationMelissa C. Grenier-Davies 3. Library Synthesis and AnalyticsJing Chai 4. Chemical Ligation of Oligonucleotide Tags to Support Encoded Chemical Library SynthesisAlexander Litovchick and Anthony D. Keefe 5. On-DNA Reductive Amination and AlkylationJing Chai 6. On-DNA-1,2,3-Triazo…
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- Publisher: Humana
- ISBN-10: 1071625446
- ISBN-13: 9781071625446
- Format: 17.8 x 25.4 x 1.4 cm, hardcover
- Language: English
- SAVE -10% with code: EXTRA
DNA-Encoded Chemical Libraries (e-book) (used book) | bookbook.eu
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Preface...
Table of Contents...
Contributing Authors...
Katelyn J. Billings and Melissa C. Grenier-Davies 2. Library Synthesis: Building Block Validation
Melissa C. Grenier-Davies 3. Library Synthesis and Analytics
Jing Chai 4. Chemical Ligation of Oligonucleotide Tags to Support Encoded Chemical Library Synthesis
Alexander Litovchick and Anthony D. Keefe 5. On-DNA Reductive Amination and Alkylation
Jing Chai 6. On-DNA-1,2,3-Triazole Formation via Click Reaction
Sarah K. Scott 7. On-DNA Suzuki-Miyaura Cross-Coupling
Yun Ding 8. On-DNA Pd and Cu Promoted C-N Cross-Coupling Reactions
Xiaojie Lu and Xuan Wang 9. Palladium Promoted On-DNA Heck Reactions
Xuan Wang and Xiaojie Lu 10. Ruthenium Promoted On-DNA C-H Activation Reaction
Xuan Wang and Xiaojie Lu 11. DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles
Huang-Chi Du, Ying-Chu Chen, and Hongbing Huang 12. Condensation of DNA-Conjugated Imines with Homophthalic Anhydride for the Synthesis of Isoquinolones On-DNA
Josephine Yuen, Jing Chai, and Yun Ding 13. DNA Encoding of Natural Products
Hongtao Xu and Peixiang Ma 14. Initiating DNA-Encoded Library Synthesis with a Hexathymidine DNA Oligonucleotide
Mateja Klika Skopic, Denise dos Santos Smith, Anne Gohla, Verena B. K. Kunig, and Andreas Brunschweiger 15. One Bead-One Compound (OBOC) Peptidomimetic Encoded Library Synthesis via Split-and-Pool Methods
Claudio Aquino and Mohosin Sarkar 16. DNA Conjugates as Tool Compounds for DEL Selections
David I. Israel 17. Quantitation of DNA Encoded Libraries by qPCR
Christopher S. Kollmann 18. Target Protein Design and Pre-Selection Analysis
Qiuxia Chen and David I. Israel 19. DEL Selections Against a Soluble Protein Target
Qiuxia Chen and Junyang Zhu 20. Selection Method of DNA-Encoded Chemical Library for Irreversible Covalent Binders
Zhengrong Zhu 21. Next Generation Sequencing of DNA-Encoded Libraries
Jian Liu and You Li 22. Translation of DNA Sequence to Chemical Structure in DNA Encoded Libraries
You Li 23. Analysis of DNA-Encoded Library Screening Data: Selection of Molecules for Synthesis
Alexander L. Satz and Weiren Cui 24. High Throughput Binder Confirmation (HTBC)
Bing Xia and Jennifer D. Summerfield 25. High-Throughput Binder Confirmation Using Affinity Selection Mass Spectrometry
Eric X. Shi Subject Index List...
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328,40 €
364,89 €
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- Publisher: Humana
- ISBN-10: 1071625446
- ISBN-13: 9781071625446
- Format: 17.8 x 25.4 x 1.4 cm, hardcover
- Language: English English
Preface...
Table of Contents...
Contributing Authors...
Katelyn J. Billings and Melissa C. Grenier-Davies 2. Library Synthesis: Building Block Validation
Melissa C. Grenier-Davies 3. Library Synthesis and Analytics
Jing Chai 4. Chemical Ligation of Oligonucleotide Tags to Support Encoded Chemical Library Synthesis
Alexander Litovchick and Anthony D. Keefe 5. On-DNA Reductive Amination and Alkylation
Jing Chai 6. On-DNA-1,2,3-Triazole Formation via Click Reaction
Sarah K. Scott 7. On-DNA Suzuki-Miyaura Cross-Coupling
Yun Ding 8. On-DNA Pd and Cu Promoted C-N Cross-Coupling Reactions
Xiaojie Lu and Xuan Wang 9. Palladium Promoted On-DNA Heck Reactions
Xuan Wang and Xiaojie Lu 10. Ruthenium Promoted On-DNA C-H Activation Reaction
Xuan Wang and Xiaojie Lu 11. DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles
Huang-Chi Du, Ying-Chu Chen, and Hongbing Huang 12. Condensation of DNA-Conjugated Imines with Homophthalic Anhydride for the Synthesis of Isoquinolones On-DNA
Josephine Yuen, Jing Chai, and Yun Ding 13. DNA Encoding of Natural Products
Hongtao Xu and Peixiang Ma 14. Initiating DNA-Encoded Library Synthesis with a Hexathymidine DNA Oligonucleotide
Mateja Klika Skopic, Denise dos Santos Smith, Anne Gohla, Verena B. K. Kunig, and Andreas Brunschweiger 15. One Bead-One Compound (OBOC) Peptidomimetic Encoded Library Synthesis via Split-and-Pool Methods
Claudio Aquino and Mohosin Sarkar 16. DNA Conjugates as Tool Compounds for DEL Selections
David I. Israel 17. Quantitation of DNA Encoded Libraries by qPCR
Christopher S. Kollmann 18. Target Protein Design and Pre-Selection Analysis
Qiuxia Chen and David I. Israel 19. DEL Selections Against a Soluble Protein Target
Qiuxia Chen and Junyang Zhu 20. Selection Method of DNA-Encoded Chemical Library for Irreversible Covalent Binders
Zhengrong Zhu 21. Next Generation Sequencing of DNA-Encoded Libraries
Jian Liu and You Li 22. Translation of DNA Sequence to Chemical Structure in DNA Encoded Libraries
You Li 23. Analysis of DNA-Encoded Library Screening Data: Selection of Molecules for Synthesis
Alexander L. Satz and Weiren Cui 24. High Throughput Binder Confirmation (HTBC)
Bing Xia and Jennifer D. Summerfield 25. High-Throughput Binder Confirmation Using Affinity Selection Mass Spectrometry
Eric X. Shi Subject Index List...
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