Reviews
Description
1. RNA Interference: Story and Mechanisms
Mouldy Sioud
2. Selection of Chemical Modifications in the siRNA Seed Region That Repress Off-target Effect
Yoshiaki Kobayashi, Kengo Miyamoto, Misako Aida, and Kumiko Ui-Tei
3. Stick-based Methods for Aptamer-mediated siRNA Targeted Delivery
Silvia Catuogno, Carla Lucia Esposito, and Paloma H. Giangrande
4. Evaluation of siRNA Stability and Interaction With Serum Components Using an Agarose Gel-Based Single-Molecule FRET Labeling Method
Martina Tuttolomondo and Henrik J. Ditzel
5. Development of siRNA Therapeutics for the Treatment of Liver DiseasesAnja Holm, Marianne Bengtson Løvendorf, and Sakari Kauppinen
6. siRNA Design and GalNAc-Empowered Hepatic Targeted Delivery
Mei Lu, Mengjie Zhang, Bo Hu, and Yuanyu Huang
7. Synthesis of GalNAc-Oligonucleotide Conjugates Using GalNAc Phosphoramidite and Triple-GalNAc CPG Solid Support
Egor A. Ulashchik, Yury V. Martynenko-Makaev, Tatsiana P. Akhlamionok, Denis M. Melnik, Vadim V. Shmanai, and Timofei S. Zatsepin
8. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhancing Gene Inhibition in Mammalian Cells
Santiago Grijalvo, Sandra M. Ocampo, José Carlos Perales, and Ramon Eritja 9. Engineering of Solid Dosages Forms of siRNA-loaded Lipidoid-Polymer Hybrid Nanoparticles using a quality by Design ApproachAbhijeet Lokras, Camilla Foged, and Aneesh Thakur
10. Preparation and Characterization of siRNA-loaded Liposomes
Yang Liu and Leaf Huang
11. SiRNA Vehicles for High Endosomal Escapability
Hiroyuki Koide, Sei Yonezawa, and Tomohiro Asai
12. SiRNA Design and Delivery Based on Carbon Nanotubes
Danyang Li and Khuloud T. Al-Jamal
13. MRI-Visible Nanovehicle for Efficient siRNA Delivery
Rongrong Jin, Wencheng Zhu, Gan Lin, Gang Liu, and Hua Ai
14. Cationic Dendrimers for siRNA Delivery: An Overview of Methods for in Vitro / In Vivo Characterization
Erik Laurini, Suzana Aulica, Domenico Marson, Maurizio Fermeglia, and Sabrina Pricl
15. ITC for Characterization of Self-Assembly Process of Cationic Dendrons for siRNA Delivery
Erik Laurini, Suzana Aulic, Natasa Skoko, Domenico Marson, Maurizio Fermeglia, Sabrina Pricl
16. Cationic Dendrimers for siRNA Delivery - Computational Approaches for Characterization
Domenico Marson, Suzana Aulic, Maurizio Fermeglia, Erik Laurini, and Sabrina Pricl
17. Fundamental and Practical Aspects in the Formulation of Colloidal Polyelectrolyte Complexes of Chitosan and siRNA
Tim Delas and Christophe Schatz
18. Cell-Penetrating Peptides Delivering siRNAs: An Overview
Luca Falato, Maxime Gestin, and Ãlo Langel
19. Non-Covalent Encapsulation of siRNA with Cell-penetrating PeptidesMartina Tuttolomondo and Henrik J. Ditzel
20. siRNA Therapeutics for Protein Misfolding Diseases of the Central Nervous System
Mark D. Zabel, Luke Mollnow, and Heather Bender
21. siRNA Loaded-exosomes
MarÃa Izco and Lydia Alvarez-Erviti
22. Production and Characterization of Anti-CCR5 siRNA-Loaded Polycaprolactone Nanoparticles for Topical Pre-Exposure Prophylaxis
Rafaela Ribeiro, Bruno Sarmento, and José das Neves
23. siRNA Therapeutics in Ocular Diseases
Javier Moreno-Montañés, Anne-Marie Bleau, Tamara MartÃnez, Beatriz Vargas, MarÃa Victoria González, and Ana Isabel Jimenez
24. Delivery of siRNA to the Eye: Protocol for a Feasibility Study to Assess Novel Del
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1. RNA Interference: Story and Mechanisms
Mouldy Sioud
2. Selection of Chemical Modifications in the siRNA Seed Region That Repress Off-target Effect
Yoshiaki Kobayashi, Kengo Miyamoto, Misako Aida, and Kumiko Ui-Tei
3. Stick-based Methods for Aptamer-mediated siRNA Targeted Delivery
Silvia Catuogno, Carla Lucia Esposito, and Paloma H. Giangrande
4. Evaluation of siRNA Stability and Interaction With Serum Components Using an Agarose Gel-Based Single-Molecule FRET Labeling Method
Martina Tuttolomondo and Henrik J. Ditzel
5. Development of siRNA Therapeutics for the Treatment of Liver DiseasesAnja Holm, Marianne Bengtson Løvendorf, and Sakari Kauppinen
6. siRNA Design and GalNAc-Empowered Hepatic Targeted Delivery
Mei Lu, Mengjie Zhang, Bo Hu, and Yuanyu Huang
7. Synthesis of GalNAc-Oligonucleotide Conjugates Using GalNAc Phosphoramidite and Triple-GalNAc CPG Solid Support
Egor A. Ulashchik, Yury V. Martynenko-Makaev, Tatsiana P. Akhlamionok, Denis M. Melnik, Vadim V. Shmanai, and Timofei S. Zatsepin
8. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhancing Gene Inhibition in Mammalian Cells
Santiago Grijalvo, Sandra M. Ocampo, José Carlos Perales, and Ramon Eritja 9. Engineering of Solid Dosages Forms of siRNA-loaded Lipidoid-Polymer Hybrid Nanoparticles using a quality by Design ApproachAbhijeet Lokras, Camilla Foged, and Aneesh Thakur
10. Preparation and Characterization of siRNA-loaded Liposomes
Yang Liu and Leaf Huang
11. SiRNA Vehicles for High Endosomal Escapability
Hiroyuki Koide, Sei Yonezawa, and Tomohiro Asai
12. SiRNA Design and Delivery Based on Carbon Nanotubes
Danyang Li and Khuloud T. Al-Jamal
13. MRI-Visible Nanovehicle for Efficient siRNA Delivery
Rongrong Jin, Wencheng Zhu, Gan Lin, Gang Liu, and Hua Ai
14. Cationic Dendrimers for siRNA Delivery: An Overview of Methods for in Vitro / In Vivo Characterization
Erik Laurini, Suzana Aulica, Domenico Marson, Maurizio Fermeglia, and Sabrina Pricl
15. ITC for Characterization of Self-Assembly Process of Cationic Dendrons for siRNA Delivery
Erik Laurini, Suzana Aulic, Natasa Skoko, Domenico Marson, Maurizio Fermeglia, Sabrina Pricl
16. Cationic Dendrimers for siRNA Delivery - Computational Approaches for Characterization
Domenico Marson, Suzana Aulic, Maurizio Fermeglia, Erik Laurini, and Sabrina Pricl
17. Fundamental and Practical Aspects in the Formulation of Colloidal Polyelectrolyte Complexes of Chitosan and siRNA
Tim Delas and Christophe Schatz
18. Cell-Penetrating Peptides Delivering siRNAs: An Overview
Luca Falato, Maxime Gestin, and Ãlo Langel
19. Non-Covalent Encapsulation of siRNA with Cell-penetrating PeptidesMartina Tuttolomondo and Henrik J. Ditzel
20. siRNA Therapeutics for Protein Misfolding Diseases of the Central Nervous System
Mark D. Zabel, Luke Mollnow, and Heather Bender
21. siRNA Loaded-exosomes
MarÃa Izco and Lydia Alvarez-Erviti
22. Production and Characterization of Anti-CCR5 siRNA-Loaded Polycaprolactone Nanoparticles for Topical Pre-Exposure Prophylaxis
Rafaela Ribeiro, Bruno Sarmento, and José das Neves
23. siRNA Therapeutics in Ocular Diseases
Javier Moreno-Montañés, Anne-Marie Bleau, Tamara MartÃnez, Beatriz Vargas, MarÃa Victoria González, and Ana Isabel Jimenez
24. Delivery of siRNA to the Eye: Protocol for a Feasibility Study to Assess Novel Del
Reviews