Animal Models of Dementia (e-book) (used book) | bookbook.eu

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Part I: Animal Modeling: General and Ethical Aspects and Drug Discovery Pipeline 1. General Introduction to Animal Models of Human Conditions Peter Paul De Deyn and Debby Van Dam 2. Animal Models of Dementia: Ethical Considerations I. Anna S. Olsson and Peter Sandøe 3. The Role of Rodent Models in the Drug Discovery Pipeline for Dementia Debby Van Dam and Peter Paul De Deyn Part II: Methodological Considerations when Developing Animal Models of Dementia 4. Species, Strain, and Gender Issues in the Development and Validation of Animal Models of Dementia Annemie Van Dijck, Debby Van Dam, and Peter Paul De Deyn 5. Transgenic and Gene Targeted Models of Dementia Ronald A. Conlon 6. Transgenic Animals and Intellectual Property Concerns Susan L. Stoddard and James A. Rogers, III Part III: Validation of Animal Models of Dementia 7. Pathological Validation of Animal Models of Dementia Daniel Pirici, Christine Van Broeckhoven, and Samir Kumar-Singh 8. Behavioral Validation in Animal Models of Dementia Debby Van Dam, Annemie Van Dijck, and Peter Paul De Deyn 9. Pharmacological Validation in Animal Models of Dementia Hugo Geerts 10. Validation of Animal Models of Dementia: Neurochemical Aspects Giancarlo Pepeu and Maria Cristina Rosi 11. Validation of Dementia Models Employing Neuroimaging Techniques Greet Vanhoutte, Adriaan Campo, and Annemie Van der Linden Part IV: Animal Models of Alzheimer's Disease 12. Drosophila melanogaster as a Model Organism for Dementia Maria E. Giannakou and Damian C. Crowther 13. Caenorhabditis elegans as a Model Organism for Dementia Tjakko J. van Ham and Ellen A.A. Nollen 14. Zebrafish (Danio rerio) as a Model Organism for Dementia Rob Willemsen, Sandra van 't Padje, John C. van Swieten, and Ben A. Oostra 15. Spontaneous Vertebrate Models of Alzheimer Dementia: Selectively Bred Strains (SAM Strains) Renã A. Sowell and D. Allan Butterfield 16. Lesion-Induced Vertebrate Models of Alzheimer Dementia Adolfo Toledano and Maria Isabel Álvarez 17. Aβ Infusion and Related Models of Alzheimer Dementia Patricia A. Lawlor and Deborah Young 18. APP-Based Transgenic Models: The PDAPP Model Jacob M. Basak and David M. Holtzman 19. APP-Based Transgenic Models: The Tg2576 Model Robert M.J. Deacon 20. APP-Based Transgenic Models: The APP23 Model Debby Van Dam and Peter Paul De Deyn 21. Presenilin-Based Transgenic Models of Alzheimer's Dementia Yuji Yoshiike and Akihiko Takashima 22. APOE-Based Models of "Pre-Dementia" Patrick M. Sullivan 23. TAU Models Nicolas Sergeant and Luc Buée 24. The 3xTg-AD Mouse Model: Reproducing and Modulating Plaque and Tangle Pathology Michael Sy, Masashi Kitazawa, and Frank LaFerla Part V: Animal Models of Non-Alzheimer Neurodegenerative Disease 25. Cognitive Dysfunction in Genetic Mouse Models of Parkinsonism Sheila M. Fleming, J. David Jentsch, and Marie-Françoise Chesselet 26. Mouse Models of Metachromatic Leukodystrophy and Adrenoleukodystrophy Patrick Aubourg, Caroline Sevin, and Nathalie Cartier 27. Animal Models of Amyotrophic Lateral Sclerosis Ludo Van Den Bosch 28. Animal Models of Frontotemporal Dementia Hana N. Dawson and Daniel T. Laskowitz Part VI: Animal Models of Vascular Dementia 29. CADASIL: Molecular Mechanisms and Animal Models Karl J. Fryxell 30. Spontaneously Hypertensive Rat (SHR): An Animal Model of Vascular Brain Disorder Francesco Amenta and Daniele Tomassoni Part VII: Animal Models of Normal Pressure Hydrocephalus 31. Animals Models of Normal Pressure Hydrocephalus Petra M. Klinge Part VIII: Animal Models of Traumatic Dementia 32. Animal Models of Traumatically-Induced Dementia Jennifer E. Slemmer, Mohammed Z. Hossain, and John T. Weber Part IX: Animal Models of Toxic Dementia 33. Animal Models of Alcohol-Induced Dementia Angela Maria Ribeiro and Silvia R. Castanheira Pereira 34. Animal Models of Metallic Dementia Luigi F. Rodella