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- Author: Atul Bhardwaj
- Publisher: LAP Lambert Academic Publishing
- ISBN-10: 3848498936
- ISBN-13: 9783848498932
- Format: 15.2 x 22.9 x 0.4 cm, softcover
- Language: English
- SAVE -10% with code: EXTRA
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Description
This book is focused on the development of non-steroidal anti-inflammatory drugs (NSAIDs); the biological target of these drugs is cyclooxygenase (COX) enzyme, which exists in two closely related isoforms viz. COX-1and COX-2. Based on the housekeeping functions of COX-1isoform and pathophysiological roles COX-2 isoform, the selective inhibition of COX-2 is desirable. NSAIDs like aspirin, ibuprofen, indomethacin, diclofenac, celecoxib, rofecoxib etc. exert their anti-inflammatory effects through the selective/non-selective inhibition of COX-1and/or COX-2 enzymes.
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- Author: Atul Bhardwaj
- Publisher: LAP Lambert Academic Publishing
- ISBN-10: 3848498936
- ISBN-13: 9783848498932
- Format: 15.2 x 22.9 x 0.4 cm, softcover
- Language: English English
This book is focused on the development of non-steroidal anti-inflammatory drugs (NSAIDs); the biological target of these drugs is cyclooxygenase (COX) enzyme, which exists in two closely related isoforms viz. COX-1and COX-2. Based on the housekeeping functions of COX-1isoform and pathophysiological roles COX-2 isoform, the selective inhibition of COX-2 is desirable. NSAIDs like aspirin, ibuprofen, indomethacin, diclofenac, celecoxib, rofecoxib etc. exert their anti-inflammatory effects through the selective/non-selective inhibition of COX-1and/or COX-2 enzymes.
Reviews